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Purkinje Cell Compartmentation in the Cerebellum of the Lysosomal Acid Phosphatase 2 Mutant Mouse (Nax - Naked-Ataxia Mutant Mouse)

The Acp2 gene encodes the beta subunit of lysosomal acid phosphatase, which is an isoenzyme that hydrolyzes orthophosphoric monoesters. In mice, a spontaneous mutation in Acp2 results in severe cerebellar defects. These include a reduced size, abnormal lobulation, and an apparent anterior cerebellar...

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Detalles Bibliográficos
Autores principales:	Bailey, Karen, Rahimi Balaei, Maryam, Mannan, Ashraf, Del Bigio, Marc R., Marzban, Hassan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983142/ https://www.ncbi.nlm.nih.gov/pubmed/24722417 http://dx.doi.org/10.1371/journal.pone.0094327

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