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Chemical Derivatives of a Small Molecule Deubiquitinase Inhibitor Have Antiviral Activity against Several RNA Viruses

Most antiviral treatment options target the invading pathogen and unavoidably encounter loss of efficacy as the pathogen mutates to overcome replication restrictions. A good strategy for circumventing drug resistance, or for pathogens without treatment options, is to target host cell proteins that a...

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Detalles Bibliográficos
Autores principales: Gonzalez-Hernandez, Marta J., Pal, Anupama, Gyan, Kofi E., Charbonneau, Marie-Eve, Showalter, Hollis D., Donato, Nicholas J., O'Riordan, Mary, Wobus, Christiane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983190/
https://www.ncbi.nlm.nih.gov/pubmed/24722666
http://dx.doi.org/10.1371/journal.pone.0094491

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