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Mycobacterium tuberculosis Rv3402c Enhances Mycobacterial Survival within Macrophages and Modulates the Host Pro-Inflammatory Cytokines Production via NF-Kappa B/ERK/p38 Signaling
Intracellular survival plays a central role in the pathogenesis of Mycobacterium tuberculosis, a process which depends on an array of virulence factors to colonize and replicate within the host. The M. tuberculosis iron regulated open reading frame (ORF) rv3402c, encoding a conserved hypothetical pr...
Autores principales: | Li, Wu, Zhao, Quanju, Deng, Wanyan, Chen, Tian, Liu, Minqiang, Xie, Jianping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983203/ https://www.ncbi.nlm.nih.gov/pubmed/24722253 http://dx.doi.org/10.1371/journal.pone.0094418 |
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