Cargando…

Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression

BACKGROUND: The phosphatidylinositol 3-kinase–regulated protein kinase, Akt, plays an important role in the initiation and progression of human cancer. Mammalian cells express three Akt isoforms (Akt1–3), which are encoded by distinct genes. Despite sharing a high degree of amino acid identity, phen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linnerth-Petrik, Nicolle M., Santry, Lisa A., Petrik, James J., Wootton, Sarah K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983215/ https://www.ncbi.nlm.nih.gov/pubmed/24722238 http://dx.doi.org/10.1371/journal.pone.0094595

Ejemplares similares

Akt isoform specific effects in ovarian cancer progression
por: Linnerth-Petrik, Nicolle M., et al.
Publicado: (2016)

Adeno-Associated Virus Vector Mediated Expression of an Oncogenic Retroviral Envelope Protein Induces Lung Adenocarcinomas in Immunocompetent Mice
por: Linnerth-Petrik, Nicolle M., et al.
Publicado: (2012)

Jaagsiekte sheep retrovirus detected in human lung cancer tissue arrays
por: Linnerth-Petrik, Nicolle M, et al.
Publicado: (2014)

Extracellular Matrix Proteins and Tumor Angiogenesis
por: Campbell, N. E., et al.
Publicado: (2010)

Experimental transmission of enzootic nasal adenocarcinoma in sheep
por: Walsh, Scott R, et al.
Publicado: (2013)

Quantifying Antigen-Specific T Cell Responses When Using Antigen-Agnostic Immunotherapies
por: van Vloten, Jacob P., et al.
Publicado: (2019)

Production and Purification of High-Titer Newcastle Disease Virus for Use in Preclinical Mouse Models of Cancer
por: Santry, Lisa A., et al.
Publicado: (2017)

Production and purification of high-titer OrfV for preclinical studies in vaccinology and cancer therapy
por: van Vloten, Jacob P., et al.
Publicado: (2021)

Normalizing Tumor Vasculature to Reduce Hypoxia, Enhance Perfusion, and Optimize Therapy Uptake
por: Matuszewska, Kathy, et al.
Publicado: (2021)

RECK isoforms have opposing effects on cell migration
por: Lee, Ha Neul, et al.
Publicado: (2018)

Surgical management of gastrointestinal stromal tumors: a single center experience
por: Poškus, Eligijus, et al.
Publicado: (2014)

SynGAP isoforms exert opposing effects on synaptic strength
por: McMahon, A.C., et al.
Publicado: (2012)

Characteristics and outcomes of gastroduodenal ulcer bleeding: a single-centre experience in Lithuania
por: Petrik, Pavel, et al.
Publicado: (2017)

Characterization of the Impact of Oncolytic Vesicular Stomatitis Virus on the Trafficking, Phenotype, and Antigen Presentation Potential of Neutrophils and Their Ability to Acquire a Non-Structural Viral Protein
por: Stegelmeier, Ashley A., et al.
Publicado: (2020)

Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis
por: Mühlethaler-Mottet, A, et al.
Publicado: (2011)

MBNL1 alternative splicing isoforms play opposing roles in cancer
por: Tabaglio, Tommaso, et al.
Publicado: (2018)

Mutant p53, the Mevalonate Pathway and the Tumor Microenvironment Regulate Tumor Response to Statin Therapy
por: Pereira, Madison, et al.
Publicado: (2022)

Oncolytic Orf virus licenses NK cells via cDC1 to activate innate and adaptive antitumor mechanisms and extends survival in a murine model of late-stage ovarian cancer
por: van Vloten, Jacob P, et al.
Publicado: (2022)

Quantifying Antibody Responses Induced by Antigen-Agnostic Immunotherapies
por: van Vloten, Jacob P., et al.
Publicado: (2019)

Characterizing Endocrine Status, Tumor Hypoxia and Immunogenicity for Therapy Success in Epithelial Ovarian Cancer
por: Pereira, Madison, et al.
Publicado: (2021)

Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression
por: Choi, Soyoung, et al.
Publicado: (2019)

Leaf physiological and morphological constraints of water-use efficiency in C(3) plants
por: Petrík, Peter, et al.
Publicado: (2023)

Akt isoforms in vascular disease
por: Yu, Haixiang, et al.
Publicado: (2015)

Akt isoforms in the immune system
por: Guerau-de-Arellano, Mireia, et al.
Publicado: (2022)

Multiplex flow cytometry-based assay for quantifying tumor- and virus-associated antibodies induced by immunotherapies
por: Minott, Jessica A., et al.
Publicado: (2022)

Opposing effects of DNA on proteolysis of a replication initiator
por: Kubik, Slawomir, et al.
Publicado: (2012)

Diverse involvement of isoforms and gene aberrations of Akt in human lung carcinomas
por: Dobashi, Yoh, et al.
Publicado: (2015)

Prognostic value of AKT isoforms in non-small cell lung adenocarcinoma
por: Khurana, Sahil, et al.
Publicado: (2023)

DNA methylation-mediated differential expression of DLX4 isoforms has opposing roles in leukemogenesis
por: Zhou, Jing-dong, et al.
Publicado: (2022)

Resilient entrepreneurs? — revisiting the relationship between the Big Five and self-employment
por: Runst, Petrik, et al.
Publicado: (2022)

Real-Time Ellipsometry at High and Low Temperatures
por: Mukherjee, Deshabrato, et al.
Publicado: (2023)

The effects of polycyclic aromatic compounds (PACs) on mammalian ovarian function
por: Perono, Genevieve A, et al.
Publicado: (2022)

Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors
por: Baek, Hye Jung, et al.
Publicado: (2018)

BdGT43B2 functions in xylan biosynthesis and is essential for seedling survival in Brachypodium distachyon
por: Petrik, Deborah L., et al.
Publicado: (2020)

Perspective: Of Mice and Men – How Widespread Is Adult Neurogenesis?
por: Petrik, David, et al.
Publicado: (2019)

Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer
por: Chellappa, Karthikeyani, et al.
Publicado: (2016)

Opposing Effects of Indomethacin and Nordihydroguaiaretic Acid on Macrophage Function and Tumor Growth
por: Suzuki, Michihiro, et al.
Publicado: (1994)

Distinct functions of AKT isoforms in breast cancer: a comprehensive review
por: Hinz, Nico, et al.
Publicado: (2019)

Opposing function of mitochondrial prohibitin in aging
por: Artal-Sanz, Marta, et al.
Publicado: (2010)

The thrombospondin-1 receptor CD36 is an important mediator of ovarian angiogenesis and folliculogenesis
por: Osz, Kata, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_f2o81pj47on55la7tfjg1v4976