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Opposing Functions of Akt Isoforms in Lung Tumor Initiation and Progression

BACKGROUND: The phosphatidylinositol 3-kinase–regulated protein kinase, Akt, plays an important role in the initiation and progression of human cancer. Mammalian cells express three Akt isoforms (Akt1–3), which are encoded by distinct genes. Despite sharing a high degree of amino acid identity, phen...

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Detalles Bibliográficos
Autores principales:	Linnerth-Petrik, Nicolle M., Santry, Lisa A., Petrik, James J., Wootton, Sarah K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983215/ https://www.ncbi.nlm.nih.gov/pubmed/24722238 http://dx.doi.org/10.1371/journal.pone.0094595

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