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Development of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced Raman Scattering
[Image: see text] In the ongoing search for ever-brighter surface-enhanced Raman scattering (SERS) nanoprobes, gold nanostars (AuNSs) have emerged as one of the best geometries for producing SERS in a nonaggregated state. Despite their high enhancement factor, optical extinction from plasmon-matched...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983328/ https://www.ncbi.nlm.nih.gov/pubmed/24803974 http://dx.doi.org/10.1021/jp4091393 |
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author | Fales, Andrew M. Yuan, Hsiangkuo Vo-Dinh, Tuan |
author_facet | Fales, Andrew M. Yuan, Hsiangkuo Vo-Dinh, Tuan |
author_sort | Fales, Andrew M. |
collection | PubMed |
description | [Image: see text] In the ongoing search for ever-brighter surface-enhanced Raman scattering (SERS) nanoprobes, gold nanostars (AuNSs) have emerged as one of the best geometries for producing SERS in a nonaggregated state. Despite their high enhancement factor, optical extinction from plasmon-matched nanoparticles can greatly attenuate the overall SERS intensity. Herein, we report the development of a new hybrid bimetallic NS-based platform that exhibits superior resonant SERS (SERRS) properties. In this new nanoplatform, coating AuNSs with a subtotal layer of silver (AuNS@Ag) can further increase their SERRS brightness by an order of magnitude when being interrogated by an off-resonant excitation source. Silica-encapsulated AuNS@Ag nanoprobes were injected intradermally into a rat pelt, where SERRS was readily detected with higher signal-to-noise than nanoprobes prepared from AuNS. Moreover, these off-resonance AuNS@Ag nanoprobes did not cause any gross photothermal damage to tissue, which was observed with the plasmon-matched AuNSs. This novel SERRS-active hybrid nanoprobe exhibits high SERRS brightness and offers promising properties for future applications in sensing and molecular imaging. |
format | Online Article Text |
id | pubmed-3983328 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | American Chemical
Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-39833282014-05-07 Development of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced Raman Scattering Fales, Andrew M. Yuan, Hsiangkuo Vo-Dinh, Tuan J Phys Chem C Nanomater Interfaces [Image: see text] In the ongoing search for ever-brighter surface-enhanced Raman scattering (SERS) nanoprobes, gold nanostars (AuNSs) have emerged as one of the best geometries for producing SERS in a nonaggregated state. Despite their high enhancement factor, optical extinction from plasmon-matched nanoparticles can greatly attenuate the overall SERS intensity. Herein, we report the development of a new hybrid bimetallic NS-based platform that exhibits superior resonant SERS (SERRS) properties. In this new nanoplatform, coating AuNSs with a subtotal layer of silver (AuNS@Ag) can further increase their SERRS brightness by an order of magnitude when being interrogated by an off-resonant excitation source. Silica-encapsulated AuNS@Ag nanoprobes were injected intradermally into a rat pelt, where SERRS was readily detected with higher signal-to-noise than nanoprobes prepared from AuNS. Moreover, these off-resonance AuNS@Ag nanoprobes did not cause any gross photothermal damage to tissue, which was observed with the plasmon-matched AuNSs. This novel SERRS-active hybrid nanoprobe exhibits high SERRS brightness and offers promising properties for future applications in sensing and molecular imaging. American Chemical Society 2014-01-14 2014-02-20 /pmc/articles/PMC3983328/ /pubmed/24803974 http://dx.doi.org/10.1021/jp4091393 Text en Copyright © 2014 American Chemical Society |
spellingShingle | Fales, Andrew M. Yuan, Hsiangkuo Vo-Dinh, Tuan Development of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced Raman Scattering |
title | Development
of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced
Raman Scattering |
title_full | Development
of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced
Raman Scattering |
title_fullStr | Development
of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced
Raman Scattering |
title_full_unstemmed | Development
of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced
Raman Scattering |
title_short | Development
of Hybrid Silver-Coated Gold Nanostars for Nonaggregated Surface-Enhanced
Raman Scattering |
title_sort | development
of hybrid silver-coated gold nanostars for nonaggregated surface-enhanced
raman scattering |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983328/ https://www.ncbi.nlm.nih.gov/pubmed/24803974 http://dx.doi.org/10.1021/jp4091393 |
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