Cargando…

Electrostatic Unfolding and Interactions of Albumin Driven by pH Changes: A Molecular Dynamics Study

[Image: see text] A better understanding of protein aggregation is bound to translate into critical advances in several areas, including the treatment of misfolded protein disorders and the development of self-assembling biomaterials for novel commercial applications. Because of its ubiquity and cli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baler, K., Martin, O. A., Carignano, M. A., Ameer, G. A., Vila, J. A., Szleifer, I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983335/ https://www.ncbi.nlm.nih.gov/pubmed/24393011 http://dx.doi.org/10.1021/jp409936v

Ejemplares similares

Albumin Hydrogels Formed by Electrostatically Triggered Self-Assembly and Their Drug Delivery Capability
por: Baler, Kevin, et al.
Publicado: (2014)

A molecular simulation approach towards the development of universal nanocarriers by studying the pH- and electrostatic-driven changes in the dynamic structure of albumin
por: Srivastav, Amit Kumar, et al.
Publicado: (2020)

Formation of Nanocomplexes between Carboxymethyl Inulin and Bovine Serum Albumin via pH-Induced Electrostatic Interaction
por: Huang, Guiying, et al.
Publicado: (2019)

The contribution of electrostatics to hydrogen exchange in the unfolded protein state
por: Dass, Rupashree, et al.
Publicado: (2021)

Sorption of ammonium and nitrate to biochars is electrostatic and pH-dependent
por: Fidel, Rivka B., et al.
Publicado: (2018)

PHEPS: web-based pH-dependent Protein Electrostatics Server
por: Kantardjiev, Alexander A., et al.
Publicado: (2006)

Interaction of Ibuprofen with Partially Unfolded Bovine Serum Albumin in the Presence of Ionic Micelles and Oligosaccharides at Different λ(ex) and pH: A Spectroscopic Analysis
por: Rout, Debasish, et al.
Publicado: (2023)

Human Plasma Very Low-Density Lipoproteins Are Stabilized by Electrostatic Interactions and Destabilized by Acidic pH
por: Guha, Madhumita, et al.
Publicado: (2011)

pH-Responsive Particle-Liquid Aggregates—Electrostatic Formation Kinetics
por: Ireland, Peter M., et al.
Publicado: (2018)

Experimental demonstration of pH-dependent electrostatic catalysis of radical reactions
por: Klinska, Marta, et al.
Publicado: (2015)

Electrostatics of Tau Protein by Molecular Dynamics
por: Castro, Tarsila G., et al.
Publicado: (2019)

Molecular Dynamics Driven Design of pH-Stabilized Mutants of MNEI, a Sweet Protein
por: Leone, Serena, et al.
Publicado: (2016)

pH-Induced Electrostatic Interaction between Polyacrylates and Amino-Functionalized Graphene Oxide on Stability and Coating Performances
por: Zhang, Wenbo, et al.
Publicado: (2021)

A fine balance of hydrophobic-electrostatic communication pathways in a pH-switching protein
por: MacKenzie, Duncan W. S., et al.
Publicado: (2022)

Role of Counterions in Constant-pH Molecular Dynamics Simulations of PAMAM Dendrimers
por: Reis, Pedro B. P. S., et al.
Publicado: (2018)

Coupling Constant pH Molecular Dynamics with Accelerated Molecular Dynamics
por: Williams, Sarah L., et al.
Publicado: (2010)

Conotoxins as Sensors of Local pH and Electrostatic Potential in the Outer Vestibule of the Sodium Channel
por: Hui, Kwokyin, et al.
Publicado: (2003)

Glycocalyx electrostatic potential profile analysis: ion, pH, steric, and charge effects.
por: Schnitzer, J. E.
Publicado: (1988)

pH and redox sensitive albumin hydrogel: A self-derived biomaterial
por: Raja, S Thirupathi Kumara, et al.
Publicado: (2015)

Proteins Adsorbing onto Surface-Modified Nanoparticles: Effect of Surface Curvature, pH, and the Interplay of Polymers and Proteins Acid–Base Equilibrium
por: Gonzalez Solveyra, Estefania, et al.
Publicado: (2022)

Coral calcification in a changing World and the interactive dynamics of pH and DIC upregulation
por: McCulloch, Malcolm T., et al.
Publicado: (2017)

Dynamic Equilibria of Short-Range Electrostatic Interactions at Molecular Interfaces of Protein–DNA Complexes
por: Chen, Chuanying, et al.
Publicado: (2015)

Thermal, Chemical and pH Induced Unfolding of Turmeric Root Lectin: Modes of Denaturation
por: Biswas, Himadri, et al.
Publicado: (2014)

Scalable Constant pH Molecular Dynamics in GROMACS
por: Aho, Noora, et al.
Publicado: (2022)

Dynamical aspects of electrostatic double layers
por: Raadu, M A, et al.
Publicado: (1987)

Are the Clinical Presentations (Phenotypes) of Gitelman’s and Bartter’s Syndromes Gene Mutations Driven by Their Effects on Intracellular pH, Their “pH” Enotype?
por: Calò, Lorenzo A, et al.
Publicado: (2020)

Molecular dynamics study on the effects of charged amino acid distribution under low pH condition to the unfolding of hen egg white lysozyme and formation of beta strands
por: Zein, Husnul Fuad, et al.
Publicado: (2022)

Constant pH Molecular Dynamics in Explicit Solvent with λ-Dynamics
por: Donnini, Serena, et al.
Publicado: (2011)

Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics
por: Shtykova, Eleonora V., et al.
Publicado: (2017)

Effect of pH on the influenza fusion peptide properties unveiled by constant-pH molecular dynamics simulations combined with experiment
por: Lousa, Diana, et al.
Publicado: (2020)

pH-Induced Local Unfolding of the Phl p 6 Pollen Allergen From cpH-MD
por: Hofer, Florian, et al.
Publicado: (2021)

Self-Organization Dynamics of Collagen-like Peptides Crosslinking Is Driven by Rose-Bengal-Mediated Electrostatic Bridges
por: Rosales-Rojas, Roberto, et al.
Publicado: (2022)

Molecular dynamics simulation of RNA pseudoknot unfolding pathway
por: Guo, Yun, et al.
Publicado: (2013)

Electrocatalytic Reaction Driven Flow: Role of pH in Flow Reversal
por: Ashaju, Abimbola A., et al.
Publicado: (2021)

Constant pH Coarse-Grained Molecular Dynamics with Stochastic Charge Neutralization
por: van Teijlingen, Alexander, et al.
Publicado: (2022)

Albumin–Hyaluronan Interactions: Influence of Ionic Composition Probed by Molecular Dynamics
por: Bełdowski, Piotr, et al.
Publicado: (2021)

Protocols Utilizing Constant pH Molecular Dynamics to Compute pH-Dependent Binding Free Energies
por: Kim, M. Olivia, et al.
Publicado: (2014)

Electrostatically Driven Guanidinium Interaction Domains that Control Hydrogel-Mediated Protein Delivery In Vivo
por: Miller, Stephen E., et al.
Publicado: (2019)

Coarse-Grained Molecular Dynamics of pH-Sensitive Lipids
por: Lado-Touriño, Isabel, et al.
Publicado: (2023)

Reversible Aggregation of Molecular-Like Fluorophores Driven by Extreme pH in Carbon Dots
por: Mura, Stefania, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_a4p1odcva6ttdavc6cf1r5bgpi