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Secondary Structure, Backbone Dynamics, and Structural Topology of Phospholamban and Its Phosphorylated and Arg9Cys-Mutated Forms in Phospholipid Bilayers Utilizing (13)C and (15)N Solid-State NMR Spectroscopy

[Image: see text] Phospholamban (PLB) is a membrane protein that regulates heart muscle relaxation rates via interactions with the sarcoplasmic reticulum Ca(2+) ATPase (SERCA). When PLB is phosphorylated or Arg9Cys (R9C) is mutated, inhibition of SERCA is relieved. (13)C and (15)N solid-state NMR sp...

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Detalles Bibliográficos
Autores principales:	Yu, Xueting, Lorigan, Gary A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983341/ https://www.ncbi.nlm.nih.gov/pubmed/24511878 http://dx.doi.org/10.1021/jp500316s

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