Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells

[Image: see text] DNA methyltransferases (DNMTs) are important enzymes involved in epigenetic control of gene expression and represent valuable targets in cancer chemotherapy. A number of nucleoside DNMT inhibitors (DNMTi) have been studied in cancer, including in cancer stem cells, and two of them...

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Detalles Bibliográficos
Autores principales: Valente, Sergio, Liu, Yiwei, Schnekenburger, Michael, Zwergel, Clemens, Cosconati, Sandro, Gros, Christina, Tardugno, Maria, Labella, Donatella, Florean, Cristina, Minden, Steven, Hashimoto, Hideharu, Chang, Yanqi, Zhang, Xing, Kirsch, Gilbert, Novellino, Ettore, Arimondo, Paola B., Miele, Evelina, Ferretti, Elisabetta, Gulino, Alberto, Diederich, Marc, Cheng, Xiaodong, Mai, Antonello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983372/
https://www.ncbi.nlm.nih.gov/pubmed/24387159
http://dx.doi.org/10.1021/jm4012627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983372/
https://www.ncbi.nlm.nih.gov/pubmed/24387159
http://dx.doi.org/10.1021/jm4012627

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