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Elucidating Molecular Motion through Structural and Dynamic Filters of Energy-Minimized Conformer Ensembles

[Image: see text] Complex RNA structures are constructed from helical segments connected by flexible loops that move spontaneously and in response to binding of small molecule ligands and proteins. Understanding the conformational variability of RNA requires the characterization of the coupled time...

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Detalles Bibliográficos
Autores principales: Emani, Prashant S., Bardaro, Michael F., Huang, Wei, Aragon, Sergio, Varani, Gabriele, Drobny, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983377/
https://www.ncbi.nlm.nih.gov/pubmed/24479561
http://dx.doi.org/10.1021/jp409386t