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Elucidating Molecular Motion through Structural and Dynamic Filters of Energy-Minimized Conformer Ensembles
[Image: see text] Complex RNA structures are constructed from helical segments connected by flexible loops that move spontaneously and in response to binding of small molecule ligands and proteins. Understanding the conformational variability of RNA requires the characterization of the coupled time...
Autores principales: | Emani, Prashant S., Bardaro, Michael F., Huang, Wei, Aragon, Sergio, Varani, Gabriele, Drobny, Gary P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983377/ https://www.ncbi.nlm.nih.gov/pubmed/24479561 http://dx.doi.org/10.1021/jp409386t |
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