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Focal adhesion kinase regulates the activity of the osmosensitive transcription factor TonEBP/NFAT5 under hypertonic conditions

TonEBP/NFAT5 is a major regulator of the urinary concentrating process and is essential for the osmoadaptation of renal medullary cells. Focal adhesion kinase (FAK) is a mechanosensitive non-receptor protein tyrosine kinase expressed abundantly in the renal medulla. Since osmotic stress causes cell...

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Detalles Bibliográficos
Autores principales:	Neuhofer, Wolfgang, Küper, Christoph, Lichtnekert, Julia, Holzapfel, Konstantin, Rupanagudi, Khader V., Fraek, Maria-Luisa, Bartels, Helmut, Beck, Franz-Xaver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983490/ https://www.ncbi.nlm.nih.gov/pubmed/24772088 http://dx.doi.org/10.3389/fphys.2014.00123

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