Sequence signatures extracted from proximal promoters can be used to predict distal enhancers

BACKGROUND: Gene expression is controlled by proximal promoters and distal regulatory elements such as enhancers. While the activity of some promoters can be invariant across tissues, enhancers tend to be highly tissue-specific. RESULTS: We compiled sets of tissue-specific promoters based on gene ex...

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Detalles Bibliográficos
Autores principales: Taher, Leila, Smith, Robin P, Kim, Mee J, Ahituv, Nadav, Ovcharenko, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983659/
https://www.ncbi.nlm.nih.gov/pubmed/24156763
http://dx.doi.org/10.1186/gb-2013-14-10-r117

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