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Protection from lethal challenge in a neonatal mouse model by circulating recombinant form coxsackievirus A16 vaccine candidates

Circulating coxsackievirus A16 (CA16) is a major cause of hand, foot and mouth disease (HFMD) in South-east Asia. At present, there is no vaccine against CA16. Pathogenic animal models that are sensitive to diverse circulating CA16 viruses would be desirable for vaccine development and evaluation. I...

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Detalles Bibliográficos
Autores principales: Li, Jingliang, Chang, Junliang, Liu, Xin, Yang, Jiaxin, Guo, Haoran, Wei, Wei, Zhang, Wenyan, Yu, Xiao-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983757/
https://www.ncbi.nlm.nih.gov/pubmed/24496826
http://dx.doi.org/10.1099/vir.0.063560-0