A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view

ABSTRACT: Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of ca...

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Detalles Bibliográficos
Autores principales: Shin, Ok Ran, Kim, Yang Ree, Ban, Tae-hyun, Lim, Taeseok, Han, Tae Hee, Kim, Su Yeon, Seo, Kyung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983880/
https://www.ncbi.nlm.nih.gov/pubmed/24641870
http://dx.doi.org/10.1186/1746-1596-9-62
Descripción
Sumario:ABSTRACT: Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. He had a history of cat bite on the left hand dorsum. On excision, the lymph node showed follicular hyperplasia, stellate microabscesses with a rim of granulomatous inflammation. Warthin-Starry silver staining showed many clumps of silver-stained bacilli within the necrotic foci. Serological tests were negative. Diagnosis was established by PCR analysis. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1877499238123059

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