A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view

ABSTRACT: Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of ca...

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Autores principales: Shin, Ok Ran, Kim, Yang Ree, Ban, Tae-hyun, Lim, Taeseok, Han, Tae Hee, Kim, Su Yeon, Seo, Kyung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983880/
https://www.ncbi.nlm.nih.gov/pubmed/24641870
http://dx.doi.org/10.1186/1746-1596-9-62
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author Shin, Ok Ran
Kim, Yang Ree
Ban, Tae-hyun
Lim, Taeseok
Han, Tae Hee
Kim, Su Yeon
Seo, Kyung Jin
author_facet Shin, Ok Ran
Kim, Yang Ree
Ban, Tae-hyun
Lim, Taeseok
Han, Tae Hee
Kim, Su Yeon
Seo, Kyung Jin
author_sort Shin, Ok Ran
collection PubMed
description ABSTRACT: Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. He had a history of cat bite on the left hand dorsum. On excision, the lymph node showed follicular hyperplasia, stellate microabscesses with a rim of granulomatous inflammation. Warthin-Starry silver staining showed many clumps of silver-stained bacilli within the necrotic foci. Serological tests were negative. Diagnosis was established by PCR analysis. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1877499238123059
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spelling pubmed-39838802014-04-12 A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view Shin, Ok Ran Kim, Yang Ree Ban, Tae-hyun Lim, Taeseok Han, Tae Hee Kim, Su Yeon Seo, Kyung Jin Diagn Pathol Case Report ABSTRACT: Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. He had a history of cat bite on the left hand dorsum. On excision, the lymph node showed follicular hyperplasia, stellate microabscesses with a rim of granulomatous inflammation. Warthin-Starry silver staining showed many clumps of silver-stained bacilli within the necrotic foci. Serological tests were negative. Diagnosis was established by PCR analysis. VIRTUAL SLIDES: The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1877499238123059 BioMed Central 2014-03-19 /pmc/articles/PMC3983880/ /pubmed/24641870 http://dx.doi.org/10.1186/1746-1596-9-62 Text en Copyright © 2014 Shin et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Shin, Ok Ran
Kim, Yang Ree
Ban, Tae-hyun
Lim, Taeseok
Han, Tae Hee
Kim, Su Yeon
Seo, Kyung Jin
A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
title A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
title_full A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
title_fullStr A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
title_full_unstemmed A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
title_short A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
title_sort case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983880/
https://www.ncbi.nlm.nih.gov/pubmed/24641870
http://dx.doi.org/10.1186/1746-1596-9-62
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