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The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1

RNA polymerase II (PolII) transcribes RNA within a chromatin context, with nucleosomes acting as barriers to transcription. Despite these barriers, transcription through chromatin in vivo is highly efficient, suggesting the existence of factors that overcome this obstacle. To increase the resolution...

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Detalles Bibliográficos
Autores principales:	Skene, Peter J, Hernandez, Aaron E, Groudine, Mark, Henikoff, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Genes and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983905/ https://www.ncbi.nlm.nih.gov/pubmed/24737864 http://dx.doi.org/10.7554/eLife.02042

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