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Micro-Environment Causes Reversible Changes in DNA Methylation and mRNA Expression Profiles in Patient-Derived Glioma Stem Cells

In vitro and in vivo models are widely used in cancer research. Characterizing the similarities and differences between a patient's tumor and corresponding in vitro and in vivo models is important for understanding the potential clinical relevance of experimental data generated with these model...

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Detalles Bibliográficos
Autores principales: Baysan, Mehmet, Woolard, Kevin, Bozdag, Serdar, Riddick, Gregory, Kotliarova, Svetlana, Cam, Margaret C., Belova, Galina I., Ahn, Susie, Zhang, Wei, Song, Hua, Walling, Jennifer, Stevenson, Holly, Meltzer, Paul, Fine, Howard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984100/
https://www.ncbi.nlm.nih.gov/pubmed/24728236
http://dx.doi.org/10.1371/journal.pone.0094045