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Ca(2+) Binding Enhanced Mechanical Stability of an Archaeal Crystallin

Structural topology plays an important role in protein mechanical stability. Proteins with β-sandwich topology consisting of Greek key structural motifs, for example, I27 of muscle titin and (10)FNIII of fibronectin, are mechanically resistant as shown by single-molecule force spectroscopy (SMFS). I...

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Detalles Bibliográficos
Autores principales: Ramanujam, Venkatraman, Kotamarthi, Hema Chandra, Ainavarapu, Sri Rama Koti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984160/
https://www.ncbi.nlm.nih.gov/pubmed/24728085
http://dx.doi.org/10.1371/journal.pone.0094513