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Microfluidic quadrupole and floating concentration gradient
The concept of fluidic multipoles, in analogy to electrostatics, has long been known as a particular class of solutions of the Navier-Stokes equation in potential flows, however, experimental observations of fluidic multipoles and of their characteristics have not been reported yet. Here we present...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984239/ https://www.ncbi.nlm.nih.gov/pubmed/21897375 |
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author | Qasaimeh, Mohammad A. Gervais, Thomas Juncker, David |
author_facet | Qasaimeh, Mohammad A. Gervais, Thomas Juncker, David |
author_sort | Qasaimeh, Mohammad A. |
collection | PubMed |
description | The concept of fluidic multipoles, in analogy to electrostatics, has long been known as a particular class of solutions of the Navier-Stokes equation in potential flows, however, experimental observations of fluidic multipoles and of their characteristics have not been reported yet. Here we present a two-dimensional microfluidic quadrupole and a theoretical analysis consistent with the experimental observations. The microfluidic quadrupole was formed by simultaneously injecting and aspirating fluids from two pairs of opposing apertures in a narrow gap formed between a microfluidic probe and a substrate. A stagnation point was formed at the center of the microfluidic quadrupole, and its position could be rapidly adjusted hydrodynamically. Following the injection of a solute through one of the poles, a stationary, tunable, and movable – i.e. “floating” – concentration gradient was formed at the stagnation point. Our results lay the foundation for future combined experimental and theoretical exploration of microfluidic planar multipoles including convective-diffusive phenomena. |
format | Online Article Text |
id | pubmed-3984239 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
record_format | MEDLINE/PubMed |
spelling | pubmed-39842392014-04-11 Microfluidic quadrupole and floating concentration gradient Qasaimeh, Mohammad A. Gervais, Thomas Juncker, David Nat Commun Article The concept of fluidic multipoles, in analogy to electrostatics, has long been known as a particular class of solutions of the Navier-Stokes equation in potential flows, however, experimental observations of fluidic multipoles and of their characteristics have not been reported yet. Here we present a two-dimensional microfluidic quadrupole and a theoretical analysis consistent with the experimental observations. The microfluidic quadrupole was formed by simultaneously injecting and aspirating fluids from two pairs of opposing apertures in a narrow gap formed between a microfluidic probe and a substrate. A stagnation point was formed at the center of the microfluidic quadrupole, and its position could be rapidly adjusted hydrodynamically. Following the injection of a solute through one of the poles, a stationary, tunable, and movable – i.e. “floating” – concentration gradient was formed at the stagnation point. Our results lay the foundation for future combined experimental and theoretical exploration of microfluidic planar multipoles including convective-diffusive phenomena. 2011-09-06 /pmc/articles/PMC3984239/ /pubmed/21897375 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Qasaimeh, Mohammad A. Gervais, Thomas Juncker, David Microfluidic quadrupole and floating concentration gradient |
title | Microfluidic quadrupole and floating concentration gradient |
title_full | Microfluidic quadrupole and floating concentration gradient |
title_fullStr | Microfluidic quadrupole and floating concentration gradient |
title_full_unstemmed | Microfluidic quadrupole and floating concentration gradient |
title_short | Microfluidic quadrupole and floating concentration gradient |
title_sort | microfluidic quadrupole and floating concentration gradient |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984239/ https://www.ncbi.nlm.nih.gov/pubmed/21897375 |
work_keys_str_mv | AT qasaimehmohammada microfluidicquadrupoleandfloatingconcentrationgradient AT gervaisthomas microfluidicquadrupoleandfloatingconcentrationgradient AT junckerdavid microfluidicquadrupoleandfloatingconcentrationgradient |