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TGF-β-Activated Kinase 1 (TAK1) Signaling Regulates TGF-β-Induced WNT-5A Expression in Airway Smooth Muscle Cells via Sp1 and β-Catenin
WNT-5A, a key player in embryonic development and post-natal homeostasis, has been associated with a myriad of pathological conditions including malignant, fibroproliferative and inflammatory disorders. Previously, we have identified WNT-5A as a transcriptional target of TGF-β in airway smooth muscl...
Autores principales: | Kumawat, Kuldeep, Menzen, Mark H., Slegtenhorst, Ralph M., Halayko, Andrew J., Schmidt, Martina, Gosens, Reinoud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984265/ https://www.ncbi.nlm.nih.gov/pubmed/24728340 http://dx.doi.org/10.1371/journal.pone.0094801 |
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