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Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells
The use of antibodies in therapy and diagnosis has undergone an unprecedented expansion during the past two decades. This is due in part to innovations in antibody engineering that now offer opportunities for the production of “second generation” antibodies with multiple specificities or altered val...
Autores principales: | Kang, Jeffrey C, Poovassery, Jayakumar S, Bansal, Pankaj, You, Sungyong, Manjarres, Isabel M, Ober, Raimund J, Ward, E Sally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984324/ https://www.ncbi.nlm.nih.gov/pubmed/24492289 http://dx.doi.org/10.4161/mabs.27658 |
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