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Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells

The use of antibodies in therapy and diagnosis has undergone an unprecedented expansion during the past two decades. This is due in part to innovations in antibody engineering that now offer opportunities for the production of “second generation” antibodies with multiple specificities or altered val...

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Detalles Bibliográficos
Autores principales: Kang, Jeffrey C, Poovassery, Jayakumar S, Bansal, Pankaj, You, Sungyong, Manjarres, Isabel M, Ober, Raimund J, Ward, E Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984324/
https://www.ncbi.nlm.nih.gov/pubmed/24492289
http://dx.doi.org/10.4161/mabs.27658

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