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Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library
Botulinum toxins (BoNTs) are among the most toxic substances on earth, with serotype A toxin being the most toxic substance known. They are responsible for human botulism, a disease characterized by flaccid muscle paralysis that occurs naturally through food poisoning or the colonization of the gast...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984333/ https://www.ncbi.nlm.nih.gov/pubmed/24492304 http://dx.doi.org/10.4161/mabs.27773 |