Cargando…
Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library
Botulinum toxins (BoNTs) are among the most toxic substances on earth, with serotype A toxin being the most toxic substance known. They are responsible for human botulism, a disease characterized by flaccid muscle paralysis that occurs naturally through food poisoning or the colonization of the gast...
Autores principales: | Miethe, Sebastian, Rasetti-Escargueil, Christine, Liu, Yvonne, Chahboun, Siham, Pelat, Thibaut, Avril, Arnaud, Frenzel, Andrè, Schirrmann, Thomas, Thullier, Philippe, Sesardic, Dorothea, Hust, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984333/ https://www.ncbi.nlm.nih.gov/pubmed/24492304 http://dx.doi.org/10.4161/mabs.27773 |
Ejemplares similares
-
Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E
por: Miethe, Sebastian, et al.
Publicado: (2015) -
Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B
por: Rasetti-Escargueil, Christine, et al.
Publicado: (2015) -
Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A(1) and A(2) by targeting their heavy chain
por: Avril, Arnaud, et al.
Publicado: (2015) -
Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin
por: Chahboun, Siham, et al.
Publicado: (2011) -
Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B
por: Miethe, Sebastian, et al.
Publicado: (2016)