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Detection and replication of epistasis influencing transcription in humans
Epistasis is the phenomenon whereby one polymorphism’s effect on a trait depends on other polymorphisms present in the genome. The extent to which epistasis influences complex traits(1) and contributes to their variation(2,3) is a fundamental question in evolution and human genetics. Though often de...
Autores principales: | Hemani, Gibran, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Yang, Jian, Gibson, Greg, Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Visscher, Peter M, Powell, Joseph E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984375/ https://www.ncbi.nlm.nih.gov/pubmed/24572353 http://dx.doi.org/10.1038/nature13005 |
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