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HER2/HER3 heterodimers and p21 expression are capable of predicting adjuvant trastuzumab response in HER2+ breast cancer

Human epidermal growth factor receptor 2 (HER2) plays an important role in breast cancer progression and provides predictive information for response to targeted therapy including trastuzumab although this is limited. Downstream pathways, such as PI3K/Akt, are associated with HER2/HER3 heterodimeriz...

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Detalles Bibliográficos
Autores principales:	Green, Andrew R., Barros, Fabrício F. T., Abdel-Fatah, Tarek M. A., Moseley, Paul, Nolan, Christopher C., Durham, Alice C., Rakha, Emad A., Chan, Stephen, Ellis, Ian O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2014
Materias:	Preclinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984415/ https://www.ncbi.nlm.nih.gov/pubmed/24706169 http://dx.doi.org/10.1007/s10549-014-2925-7

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