Cargando…
Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study
PURPOSE: Genital ureaplasmas are considered opportunistic pathogens of human genitourinary tract involved in adverse pregnancy sequelae and infertility. While association of Ureaplasma urealyticum with urogenital tract infections is well established, the role of Ureaplasma parvum in these infections...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984420/ https://www.ncbi.nlm.nih.gov/pubmed/24318169 http://dx.doi.org/10.1007/s00404-013-3102-7 |
_version_ | 1782311448365498368 |
---|---|
author | Urszula, Kasprzykowska Joanna, Elias Marek, Elias Beata, Mączyńska Magdalena, Sobieszczańska Beata |
author_facet | Urszula, Kasprzykowska Joanna, Elias Marek, Elias Beata, Mączyńska Magdalena, Sobieszczańska Beata |
author_sort | Urszula, Kasprzykowska |
collection | PubMed |
description | PURPOSE: Genital ureaplasmas are considered opportunistic pathogens of human genitourinary tract involved in adverse pregnancy sequelae and infertility. While association of Ureaplasma urealyticum with urogenital tract infections is well established, the role of Ureaplasma parvum in these infections is still insufficient. In the study, we compared how often cervicovaginal colonization with U. parvum is associated with the presence of these microorganisms in the upper genitourinary tract of fertile and infertile women. METHODS: We used PCR assay to determine the prevalence of U. parvum and U. urealyticum in pairs of specimens, i.e., vaginal swabs and Douglas’ pouch fluid samples from consecutive 40 women with no symptoms of genital tract infection. RESULTS: In total, 19 (47.5 %) of the 40 samples were positive for ureaplasmas. U. parvum was simultaneously detected in pairs of samples in five (55.5 %) of the nine (47.4 %) women positive in PCR assay. As many as 5 (18.5 %) of the 27 infertile women and 1 (7.7 %) of the 13 fertile women showed infection of the upper genital tract with U. parvum. CONCLUSION: The results of the study demonstrated that colonization of the lower genital tract with U. parvum can produce asymptomatic infection of the upper reproductive system in women. These findings also imply that U. parvum may be present in the upper genital tract at the time of conception and might be involved in adverse pregnancy outcomes. |
format | Online Article Text |
id | pubmed-3984420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-39844202014-04-22 Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study Urszula, Kasprzykowska Joanna, Elias Marek, Elias Beata, Mączyńska Magdalena, Sobieszczańska Beata Arch Gynecol Obstet Gynecologic Endocrinology and Reproductive Medicine PURPOSE: Genital ureaplasmas are considered opportunistic pathogens of human genitourinary tract involved in adverse pregnancy sequelae and infertility. While association of Ureaplasma urealyticum with urogenital tract infections is well established, the role of Ureaplasma parvum in these infections is still insufficient. In the study, we compared how often cervicovaginal colonization with U. parvum is associated with the presence of these microorganisms in the upper genitourinary tract of fertile and infertile women. METHODS: We used PCR assay to determine the prevalence of U. parvum and U. urealyticum in pairs of specimens, i.e., vaginal swabs and Douglas’ pouch fluid samples from consecutive 40 women with no symptoms of genital tract infection. RESULTS: In total, 19 (47.5 %) of the 40 samples were positive for ureaplasmas. U. parvum was simultaneously detected in pairs of samples in five (55.5 %) of the nine (47.4 %) women positive in PCR assay. As many as 5 (18.5 %) of the 27 infertile women and 1 (7.7 %) of the 13 fertile women showed infection of the upper genital tract with U. parvum. CONCLUSION: The results of the study demonstrated that colonization of the lower genital tract with U. parvum can produce asymptomatic infection of the upper reproductive system in women. These findings also imply that U. parvum may be present in the upper genital tract at the time of conception and might be involved in adverse pregnancy outcomes. Springer Berlin Heidelberg 2013-12-07 2014 /pmc/articles/PMC3984420/ /pubmed/24318169 http://dx.doi.org/10.1007/s00404-013-3102-7 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Gynecologic Endocrinology and Reproductive Medicine Urszula, Kasprzykowska Joanna, Elias Marek, Elias Beata, Mączyńska Magdalena, Sobieszczańska Beata Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
title | Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
title_full | Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
title_fullStr | Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
title_full_unstemmed | Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
title_short | Colonization of the lower urogenital tract with Ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
title_sort | colonization of the lower urogenital tract with ureaplasma parvum can cause asymptomatic infection of the upper reproductive system in women: a preliminary study |
topic | Gynecologic Endocrinology and Reproductive Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984420/ https://www.ncbi.nlm.nih.gov/pubmed/24318169 http://dx.doi.org/10.1007/s00404-013-3102-7 |
work_keys_str_mv | AT urszulakasprzykowska colonizationofthelowerurogenitaltractwithureaplasmaparvumcancauseasymptomaticinfectionoftheupperreproductivesysteminwomenapreliminarystudy AT joannaelias colonizationofthelowerurogenitaltractwithureaplasmaparvumcancauseasymptomaticinfectionoftheupperreproductivesysteminwomenapreliminarystudy AT marekelias colonizationofthelowerurogenitaltractwithureaplasmaparvumcancauseasymptomaticinfectionoftheupperreproductivesysteminwomenapreliminarystudy AT beatamaczynska colonizationofthelowerurogenitaltractwithureaplasmaparvumcancauseasymptomaticinfectionoftheupperreproductivesysteminwomenapreliminarystudy AT magdalenasobieszczanskabeata colonizationofthelowerurogenitaltractwithureaplasmaparvumcancauseasymptomaticinfectionoftheupperreproductivesysteminwomenapreliminarystudy |