Cargando…

Cellular reprogramming for pancreatic β-cell regeneration: clinical potential of small molecule control

Recent scientific breakthroughs in stem cell biology suggest that a sustainable treatment approach to cure diabetes mellitus (DM) can be achieved in the near future. However, the transplantation complexities and the difficulty in obtaining the stem cells from adult cells of pancreas, liver, bone mor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pandian, Ganesh N, Taniguchi, Junichi, Sugiyama, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984496/ https://www.ncbi.nlm.nih.gov/pubmed/24679123 http://dx.doi.org/10.1186/2001-1326-3-6

Ejemplares similares

A Multi‐target Small Molecule for Targeted Transcriptional Activation of Therapeutically Significant Nervous System Genes
por: Wei, Yulei, et al.
Publicado: (2016)

Strategies To Modulate Heritable Epigenetic Defects in Cellular Machinery: Lessons from Nature
por: Pandian, Ganesh N., et al.
Publicado: (2012)

A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts
por: Pandian, Ganesh N., et al.
Publicado: (2012)

Commentary: Cellular reprogramming for myocardial regeneration and beyond
por: Akhmerov, Akbarshakh, et al.
Publicado: (2020)

A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm
por: Taniguchi, Junichi, et al.
Publicado: (2017)

A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming
por: Son, Myung Jin, et al.
Publicado: (2018)

Reprogramming cell fates by small molecules
por: Ma, Xiaojie, et al.
Publicado: (2017)

A Gene Regulatory Network for Cellular Reprogramming in Plant Regeneration
por: Ikeuchi, Momoko, et al.
Publicado: (2018)

In vivo partial cellular reprogramming enhances liver plasticity and regeneration
por: Hishida, Tomoaki, et al.
Publicado: (2022)

Clinical potential of angiogenic therapy and cellular reprogramming
por: Ryan, Christopher T., et al.
Publicado: (2021)

Potential of Small Molecule–Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis Pigmentosa
por: Nakamura, Paul A., et al.
Publicado: (2016)

Enhanced Generation of Induced Cardiomyocytes Using a Small‐Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming
por: Singh, Vivek P., et al.
Publicado: (2020)

Potential Pathways to Restore β-Cell Mass: Pluripotent Stem Cells, Reprogramming, and Endogenous Regeneration
por: Baiu, Dana, et al.
Publicado: (2011)

Efficient Feeder-Free Episomal Reprogramming with Small Molecules
por: Yu, Junying, et al.
Publicado: (2011)

Reprogramming with Small Molecules instead of Exogenous Transcription Factors
por: Lin, Tongxiang, et al.
Publicado: (2015)

Intermediate cells of in vitro cellular reprogramming and in vivo tissue regeneration require desmoplakin
por: Ha, Jeongmin, et al.
Publicado: (2022)

Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules
por: Miyamoto, Kei, et al.
Publicado: (2017)

Regeneration and reprogramming compared
por: Christen, Bea, et al.
Publicado: (2010)

Reprogramming for cardiac regeneration
por: Raynaud, Christophe Michel, et al.
Publicado: (2014)

Epigenetic Control of Reprogramming and Cellular Differentiation
por: Latella, Lucia, et al.
Publicado: (2012)

Manipulation of the nucleoscaffold potentiates cellular reprogramming kinetics
por: Yang, Benjamin A., et al.
Publicado: (2023)

Transcriptome Analysis of Small Molecule–Mediated Astrocyte-to-Neuron Reprogramming
por: Ma, Ning-Xin, et al.
Publicado: (2019)

Automatic identification of small molecules that promote cell conversion and reprogramming
por: Napolitano, Francesco, et al.
Publicado: (2021)

Small-Molecule Inhibitors Overcome Epigenetic Reprogramming for Cancer Therapy
por: Xiao, Wenjing, et al.
Publicado: (2021)

Small molecules for cell reprogramming: a systems biology analysis
por: Knyazer, Anna, et al.
Publicado: (2021)

Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes
por: Tian, E, et al.
Publicado: (2016)

Potentials of Cellular Reprogramming as a Novel Strategy for Neuroregeneration
por: Fang, Lyujie, et al.
Publicado: (2018)

Cellular Reprogramming and Its Potential Application in Alzheimer’s Disease
por: Zhou, Chao, et al.
Publicado: (2022)

Hepatocytes reprogram liver macrophages involving control of TGF-β activation, influencing liver regeneration and injury
por: Wolf, Stephanie D., et al.
Publicado: (2023)

Algorithm for cellular reprogramming
por: Ronquist, Scott, et al.
Publicado: (2017)

Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration
por: Allanki, Srinivas, et al.
Publicado: (2021)

Reprogramming of human pancreatic exocrine cells to β-like cells
por: Lemper, M, et al.
Publicado: (2015)

Cellular reprogramming for clinical cartilage repair
por: Driessen, Britta J.H., et al.
Publicado: (2017)

Direct Reprogramming of Mouse Fibroblasts to Neural Stem Cells by Small Molecules
por: Han, Yan-Chuang, et al.
Publicado: (2016)

Small-molecule-mediated reprogramming: a silver lining for regenerative medicine
por: Kim, Yohan, et al.
Publicado: (2020)

Application of Small Molecules in the Central Nervous System Direct Neuronal Reprogramming
por: Wang, Jingyi, et al.
Publicado: (2022)

Sebaceous gland reprogramming with a single gene, PPARG, and small molecules
por: Liu, Yiqiong, et al.
Publicado: (2023)

β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry
por: Rubini, Elisabetta, et al.
Publicado: (2020)

Sox2 Level Is a Determinant of Cellular Reprogramming Potential
por: Han, Dong Wook, et al.
Publicado: (2013)

Corrigendum: Potentials of Cellular Reprogramming as a Novel Strategy for Neuroregeneration
por: Fang, Lyujie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4pj6uhp3ppf81kupvqsmofcfmo