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Targeting Spleen Tyrosine Kinase-Bruton's Tyrosine Kinase Axis for Immunologically Mediated Glomerulonephritis

The importance of B-cell activation and immune complex-mediated Fc-receptor activation in the pathogenesis of immunologically mediated glomerulonephritis has long been recognized. The two nonreceptor tyrosine kinases, spleen tyrosine kinase (Syk) and Bruton's tyrosine kinase (Btk), are primaril...

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Detalles Bibliográficos
Autores principales:	Chen, Jin-Shuen, Chang, Li-Chien, Huang, Shyh-Jer, Cheng, Chao-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985139/ https://www.ncbi.nlm.nih.gov/pubmed/24795896 http://dx.doi.org/10.1155/2014/814869

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