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A New Nested Allele-Specific Multiplex Polymerase Chain Reaction Method for Haplotyping of VKORC1 Gene to Predict Warfarin Sensitivity

The vitamin K epoxide reductase complex 1 gene (VKORC1) is commonly assessed to predict warfarin sensitivity. In this study, a new nested allele-specific multiplex polymerase chain reaction (PCR) method that can simultaneously identify single nucleotide polymorphisms (SNPs) at VKORC1 381, 861, 5808,...

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Detalles Bibliográficos
Autores principales: Chua, Yung An, Abdullah, Wan Zaidah, Yusof, Zukurnai, Gan, Siew Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985146/
https://www.ncbi.nlm.nih.gov/pubmed/24790995
http://dx.doi.org/10.1155/2014/316310