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A Case of Acute Psychosis in an Adolescent Male
Primary hyperparathyroidism (PHPT) is a disorder of calcium homeostasis. We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985178/ https://www.ncbi.nlm.nih.gov/pubmed/24795826 http://dx.doi.org/10.1155/2014/937631 |
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author | Babar, Ghufran Alemzadeh, Ramin |
author_facet | Babar, Ghufran Alemzadeh, Ramin |
author_sort | Babar, Ghufran |
collection | PubMed |
description | Primary hyperparathyroidism (PHPT) is a disorder of calcium homeostasis. We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi scan showed a positive signal inferior to the left lobe of the thyroid gland. He had only a partial response to the initial medical and psychiatric management. The enlarged parathyroid gland was resected surgically and postoperatively serum calcium and iPTH levels normalized. The histopathology was compatible with a benign adenoma. Patient's acute psychotic symptoms resolved gradually after surgery; however he remained under psychiatric care for the behavioral issues for about 6 months after surgery. While psychosis is a rare clinical manifestation of hypercalcemia secondary to PHPT in pediatric population, it should be considered as a clinical clue in an otherwise asymptomatic pediatric patient. |
format | Online Article Text |
id | pubmed-3985178 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39851782014-05-04 A Case of Acute Psychosis in an Adolescent Male Babar, Ghufran Alemzadeh, Ramin Case Rep Endocrinol Case Report Primary hyperparathyroidism (PHPT) is a disorder of calcium homeostasis. We report the case of a 17-year-old adolescent male, who presented with an acute psychosis coinciding with severe hypercalcemia and markedly elevated intact parathyroid hormone (iPTH) level and low vitamin D level. A Sestamibi scan showed a positive signal inferior to the left lobe of the thyroid gland. He had only a partial response to the initial medical and psychiatric management. The enlarged parathyroid gland was resected surgically and postoperatively serum calcium and iPTH levels normalized. The histopathology was compatible with a benign adenoma. Patient's acute psychotic symptoms resolved gradually after surgery; however he remained under psychiatric care for the behavioral issues for about 6 months after surgery. While psychosis is a rare clinical manifestation of hypercalcemia secondary to PHPT in pediatric population, it should be considered as a clinical clue in an otherwise asymptomatic pediatric patient. Hindawi Publishing Corporation 2014 2014-03-30 /pmc/articles/PMC3985178/ /pubmed/24795826 http://dx.doi.org/10.1155/2014/937631 Text en Copyright © 2014 G. Babar and R. Alemzadeh. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Babar, Ghufran Alemzadeh, Ramin A Case of Acute Psychosis in an Adolescent Male |
title | A Case of Acute Psychosis in an Adolescent Male |
title_full | A Case of Acute Psychosis in an Adolescent Male |
title_fullStr | A Case of Acute Psychosis in an Adolescent Male |
title_full_unstemmed | A Case of Acute Psychosis in an Adolescent Male |
title_short | A Case of Acute Psychosis in an Adolescent Male |
title_sort | case of acute psychosis in an adolescent male |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985178/ https://www.ncbi.nlm.nih.gov/pubmed/24795826 http://dx.doi.org/10.1155/2014/937631 |
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