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Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

Planarian flatworms regenerate every organ after amputation. Adult pluripotent stem cells drive this ability, but how injury activates and directs stem cells into the appropriate lineages is unclear. Here we describe a single-organ regeneration assay in which ejection of the planarian pharynx is sel...

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Detalles Bibliográficos
Autores principales: Adler, Carolyn E, Seidel, Chris W, McKinney, Sean A, Sánchez Alvarado, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985184/
https://www.ncbi.nlm.nih.gov/pubmed/24737865
http://dx.doi.org/10.7554/eLife.02238