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Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever

A deterministic SEIR model of rift valley fever (RVF) with climate change parameters was considered to compute the basic reproduction number ℛ (0) and investigate the impact of temperature and precipitation on ℛ (0). To study the effect of model parameters to ℛ (0), sensitivity and elasticity analys...

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Autores principales: Mpeshe, Saul C., Luboobi, Livingstone S., Nkansah-Gyekye, Yaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985190/
https://www.ncbi.nlm.nih.gov/pubmed/24795775
http://dx.doi.org/10.1155/2014/627586
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author Mpeshe, Saul C.
Luboobi, Livingstone S.
Nkansah-Gyekye, Yaw
author_facet Mpeshe, Saul C.
Luboobi, Livingstone S.
Nkansah-Gyekye, Yaw
author_sort Mpeshe, Saul C.
collection PubMed
description A deterministic SEIR model of rift valley fever (RVF) with climate change parameters was considered to compute the basic reproduction number ℛ (0) and investigate the impact of temperature and precipitation on ℛ (0). To study the effect of model parameters to ℛ (0), sensitivity and elasticity analysis of ℛ (0) were performed. When temperature and precipitation effects are not considered, ℛ (0) is more sensitive to the expected number of infected Aedes spp. due to one infected livestock and more elastic to the expected number of infected livestock due to one infected Aedes spp. When climatic data are used, ℛ (0) is found to be more sensitive and elastic to the expected number of infected eggs laid by Aedes spp. via transovarial transmission, followed by the expected number of infected livestock due to one infected Aedes spp. and the expected number of infected Aedes spp. due to one infected livestock for both regions Arusha and Dodoma. These results call for attention to parameters regarding incubation period, the adequate contact rate of Aedes spp. and livestock, the infective periods of livestock and Aedes spp., and the vertical transmission in Aedes species.
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spelling pubmed-39851902014-05-04 Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever Mpeshe, Saul C. Luboobi, Livingstone S. Nkansah-Gyekye, Yaw Comput Math Methods Med Research Article A deterministic SEIR model of rift valley fever (RVF) with climate change parameters was considered to compute the basic reproduction number ℛ (0) and investigate the impact of temperature and precipitation on ℛ (0). To study the effect of model parameters to ℛ (0), sensitivity and elasticity analysis of ℛ (0) were performed. When temperature and precipitation effects are not considered, ℛ (0) is more sensitive to the expected number of infected Aedes spp. due to one infected livestock and more elastic to the expected number of infected livestock due to one infected Aedes spp. When climatic data are used, ℛ (0) is found to be more sensitive and elastic to the expected number of infected eggs laid by Aedes spp. via transovarial transmission, followed by the expected number of infected livestock due to one infected Aedes spp. and the expected number of infected Aedes spp. due to one infected livestock for both regions Arusha and Dodoma. These results call for attention to parameters regarding incubation period, the adequate contact rate of Aedes spp. and livestock, the infective periods of livestock and Aedes spp., and the vertical transmission in Aedes species. Hindawi Publishing Corporation 2014 2014-03-30 /pmc/articles/PMC3985190/ /pubmed/24795775 http://dx.doi.org/10.1155/2014/627586 Text en Copyright © 2014 Saul C. Mpeshe et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mpeshe, Saul C.
Luboobi, Livingstone S.
Nkansah-Gyekye, Yaw
Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever
title Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever
title_full Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever
title_fullStr Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever
title_full_unstemmed Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever
title_short Modeling the Impact of Climate Change on the Dynamics of Rift Valley Fever
title_sort modeling the impact of climate change on the dynamics of rift valley fever
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985190/
https://www.ncbi.nlm.nih.gov/pubmed/24795775
http://dx.doi.org/10.1155/2014/627586
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