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Synthesis of Brominated 2-Phenitidine Derivatives as Valuable Inhibitors of Cholinesterases for the Treatment of Alzheimer’s Disease

The present study reports the synthesis of a series N-substituted derivatives of brominated 2-phenitidine. First, the reaction of 2-phenitidine (1) with benzenesulfonyl chloride (2) in aqueous media yielded N-(2-ethoxyphenyl) benzenesulfonamide (3), which was then subjected to bromination with bromi...

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Detalles Bibliográficos
Autores principales: Abbasi, Muhammad Athar, Saeed, Amna, Aziz-ur-Rehman, Mohmmed Khan, Khalid, Ashraf, Muhammad, Ejaz, Syeda Abida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985256/
https://www.ncbi.nlm.nih.gov/pubmed/24734059

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