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Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen()()
Clostridial collagenases are among the most efficient degraders of collagen. Most clostridia are saprophytes and secrete proteases to utilize proteins in their environment as carbon sources; during anaerobic infections, collagenases play a crucial role in host colonization. Several medical and biote...
Autores principales: | Eckhard, Ulrich, Huesgen, Pitter F., Brandstetter, Hans, Overall, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985423/ https://www.ncbi.nlm.nih.gov/pubmed/24125730 http://dx.doi.org/10.1016/j.jprot.2013.10.004 |
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