Cargando…
Diazirine-Containing Photoactivatable Isoprenoid: Synthesis and Application in Studies with Isoprenylcysteine Carboxyl Methyltransferase
[Image: see text] Photoaffinity labeling is a useful technique employed to identify protein–ligand and protein–protein noncovalent interactions. Photolabeling experiments have been particularly informative for probing membrane-bound proteins where structural information is difficult to obtain. The m...
Autores principales: | Vervacke, Jeffrey S., Funk, Amy L., Wang, Yen-Chih, Strom, Mark, Hrycyna, Christine A., Distefano, Mark D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985442/ https://www.ncbi.nlm.nih.gov/pubmed/24502619 http://dx.doi.org/10.1021/jo402600b |
Ejemplares similares
-
Is isoprenylcysteine carboxyl methyltransferase the key to reverse ageing?
por: Grams, Danielle, et al.
Publicado: (2013) -
a-Factor Analogues Containing Alkyne- and Azide-Functionalized
Isoprenoids Are Efficiently Enzymatically Processed and Retain Wild-Type
Bioactivity
por: Diaz-Rodriguez, Veronica, et al.
Publicado: (2017) -
Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses
por: Yang, Woo Seok, et al.
Publicado: (2020) -
Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments †
por: Spillier, Quentin, et al.
Publicado: (2021) -
Rapid Analysis of Protein Farnesyltransferase Substrate
Specificity Using Peptide Libraries and Isoprenoid Diphosphate Analogues
por: Wang, Yen-Chih, et al.
Publicado: (2014)