Application of Quantitative Structure–Activity Relationship Models of 5-HT(1A) Receptor Binding to Virtual Screening Identifies Novel and Potent 5-HT(1A) Ligands

[Image: see text] The 5-hydroxytryptamine 1A (5-HT(1A)) serotonin receptor has been an attractive target for treating mood and anxiety disorders such as schizophrenia. We have developed binary classification quantitative structure–activity relationship (QSAR) models of 5-HT(1A) receptor binding acti...

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Detalles Bibliográficos
Autores principales: Luo, Man, Wang, Xiang Simon, Roth, Bryan L., Golbraikh, Alexander, Tropsha, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985444/
https://www.ncbi.nlm.nih.gov/pubmed/24410373
http://dx.doi.org/10.1021/ci400460q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985444/
https://www.ncbi.nlm.nih.gov/pubmed/24410373
http://dx.doi.org/10.1021/ci400460q

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