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Thioamide-Based Fluorescent Protease Sensors
[Image: see text] Thioamide quenchers can be paired with compact fluorophores to design “turn-on” fluorescent protease substrates. We have used this method to study a variety of serine-, cysteine-, carboxyl-, and metallo-proteases, including trypsin, chymotrypsin, pepsin, thermolysin, papain, and ca...
Autores principales: | Goldberg, Jacob M., Chen, Xing, Meinhardt, Nataline, Greenbaum, Doron C., Petersson, E. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985465/ https://www.ncbi.nlm.nih.gov/pubmed/24472041 http://dx.doi.org/10.1021/ja412297x |
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