Cargando…

Producing Proficient Methyl Donors from Alternative Substrates of S-Adenosylmethionine Synthetase

[Image: see text] Bacteria use quorum sensing to probe and respond to population densities in their external environment. The detection of quorum signaling molecules causes a virulence response in many pathogenic bacteria. Blocking this signaling pathway, without interfering with critical metabolic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wijayasinghe, Yasanandana S., Blumenthal, Robert M., Viola, Ronald E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985469/ https://www.ncbi.nlm.nih.gov/pubmed/24528526 http://dx.doi.org/10.1021/bi401556p

Ejemplares similares

An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated
por: Ho, Percy, et al.
Publicado: (2007)

Synthetase of the methyl donor S-adenosylmethionine from nitrogen-fixing α-rhizobia can bind functionally diverse RNA species
por: Robledo, Marta, et al.
Publicado: (2020)

Comparison of four low-cost carbapenemase detection tests and a proposal of an algorithm for early detection of carbapenemase-producing Enterobacteriaceae in resource-limited settings
por: Kumudunie, Wirittamulla Gamage Maheshika, et al.
Publicado: (2021)

Overexpression of S-Adenosylmethionine Synthetase in Recombinant Chlamydomonas for Enhanced Lipid Production
por: Kim, Jeong Hyeon, et al.
Publicado: (2023)

Sirtuins as Potential Therapeutic Targets for Mitigating Neuroinflammation Associated With Alzheimer’s Disease
por: Fernando, Kurukulasooriya Kavindya Madushani, et al.
Publicado: (2021)

Profiling The Compendium Of Changes In Saccharomyces cerevisiae Due To Mutations That Alter Availability Of The Main Methyl Donor S-Adenosylmethionine
por: Remines, McKayla, et al.
Publicado: (2023)

Substrate Profiling of Anion Methyltransferases for Promiscuous Synthesis of S‐Adenosylmethionine Analogs from Haloalkanes
por: Schülke, Kai H., et al.
Publicado: (2022)

S-Adenosylmethionine Synthetase Is Required for Cell Growth, Maintenance of G0 Phase, and Termination of Quiescence in Fission Yeast
por: Hayashi, Takeshi, et al.
Publicado: (2018)

In vitro anti-diabetic effects and phytochemical profiling of novel varieties of Cinnamomum zeylanicum (L.) extracts
por: Wariyapperuma, W.A. Niroshani M., et al.
Publicado: (2020)

Coupling S-adenosylmethionine–dependent methylation to growth: Design and uses
por: Luo, Hao, et al.
Publicado: (2019)

Excess S-adenosylmethionine inhibits methylation via catabolism to adenine
por: Fukumoto, Kazuki, et al.
Publicado: (2022)

The Biochemistry of Adenosylmethionine
por: Kraus, Jan
Publicado: (1978)

Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications
por: Mahmood, Niaz, et al.
Publicado: (2017)

An enhanced chemopreventive effect of methyl donor S-adenosylmethionine in combination with 25-hydroxyvitamin D in blocking mammary tumor growth and metastasis
por: Mahmood, Niaz, et al.
Publicado: (2020)

Plasmodium falciparum S-Adenosylmethionine Synthetase Is Essential for Parasite Survival through a Complex Interaction Network with Cytoplasmic and Nuclear Proteins
por: Musabyimana, Jean Pierre, et al.
Publicado: (2022)

Radical S-Adenosylmethionine Enzymes
por: Broderick, Joan B., et al.
Publicado: (2014)

Crystallographic and Computational Characterization of Methyl Tetrel Bonding in S-Adenosylmethionine-Dependent Methyltransferases
por: Trievel, Raymond C., et al.
Publicado: (2018)

The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease
por: King, Adrienne L., et al.
Publicado: (2016)

Immunoassay of S-adenosylmethionine and S-adenosylhomocysteine: the methylation index as a biomarker for disease and health status
por: Hao, Xiujuan, et al.
Publicado: (2016)

Resistance of Leishmania infantum to allopurinol is associated with chromosome and gene copy number variations including decrease in the S-adenosylmethionine synthetase (METK) gene copy number
por: Yasur-Landau, Daniel, et al.
Publicado: (2018)

The Barley S-Adenosylmethionine Synthetase 3 Gene HvSAMS3 Positively Regulates the Tolerance to Combined Drought and Salinity Stress in Tibetan Wild Barley
por: Ahmed, Imrul Mosaddek, et al.
Publicado: (2020)

S-Adenosylmethionine (SAM)-Dependent Methyltransferase MftM is Responsible for Methylation of the Redox Cofactor Mycofactocin
por: Ellerhorst, Mark, et al.
Publicado: (2022)

Natural history of S-adenosylmethionine-binding proteins
por: Kozbial, Piotr Z, et al.
Publicado: (2005)

Potential role of S-adenosylmethionine in osteosarcoma development
por: Shi, Hui, et al.
Publicado: (2016)

DNA methylation regulates expression of VEGF-C, and S-adenosylmethionine is effective for VEGF-C methylation and for inhibiting cancer growth
por: Da, M.X., et al.
Publicado: (2014)

Pharmacogenetics of thiopurine therapy: from thiopurine S-methyltransferase to S-adenosylmethionine
por: Mlinarič-Raščan, Irena, et al.
Publicado: (2009)

Metabolic engineering of Bacillus amyloliquefaciens for enhanced production of S-adenosylmethionine by coupling of an engineered S-adenosylmethionine pathway and the tricarboxylic acid cycle
por: Ruan, Liying, et al.
Publicado: (2019)

Depletion of S-adenosylmethionine impacts on ribosome biogenesis through hypomodification of a single rRNA methylation
por: Ishiguro, Kensuke, et al.
Publicado: (2019)

S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD
por: Guo, Tao, et al.
Publicado: (2021)

New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C(8) Substitution in Structural Analogues of S-Adenosylmethionine
por: McCloskey, Diane E., et al.
Publicado: (2009)

Structure and function study of the complex that synthesizes S-adenosylmethionine
por: Murray, Ben, et al.
Publicado: (2014)

Engineered Pichia pastoris for enhanced production of S-adenosylmethionine
por: Kamarthapu, Venu, et al.
Publicado: (2013)

S‐adenosylmethionine: A metabolite critical to the regulation of autophagy
por: Ouyang, Yang, et al.
Publicado: (2020)

Rethinking the bioavailability and cellular transport properties of S-adenosylmethionine
por: Sun, Yudong, et al.
Publicado: (2021)

Deregulation of S-adenosylmethionine biosynthesis and regeneration improves methylation in the E. coli de novo vanillin biosynthesis pathway
por: Kunjapur, Aditya M., et al.
Publicado: (2016)

Site Directed Mutagenesis of Schizosaccharomyces pombe Glutathione Synthetase Produces an Enzyme with Homoglutathione Synthetase Activity
por: Dworeck, Tamara, et al.
Publicado: (2012)

Mechanistic Studies on the Substrate-Tolerant Lanthipeptide Synthetase ProcM
por: Mukherjee, Subha, et al.
Publicado: (2014)

Insights into substrate promiscuity of human seryl-tRNA synthetase
por: Holman, Kaitlyn M., et al.
Publicado: (2017)

Paramagnetic Intermediates Generated by Radical S-Adenosylmethionine (SAM) Enzymes
por: Stich, Troy A., et al.
Publicado: (2014)

Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase
por: Bale, Shridhar, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_u5ejtp3nq5d0g9aiu33pg61s81