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Quantitative Analysis of rRNA Modifications Using Stable Isotope Labeling and Mass Spectrometry

[Image: see text] Post-transcriptional RNA modifications that are introduced during the multistep ribosome biogenesis process are essential for protein synthesis. The current lack of a comprehensive method for a fast quantitative analysis of rRNA modifications significantly limits our understanding...

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Detalles Bibliográficos
Autores principales: Popova, Anna M., Williamson, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985470/
https://www.ncbi.nlm.nih.gov/pubmed/24422502
http://dx.doi.org/10.1021/ja412084b