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Effect of Basic Cell-Penetrating Peptides on the Structural, Thermodynamic, and Hydrodynamic Properties of a Novel Drug Delivery Vector, ELP[V(5)G(3)A(2)-150]
[Image: see text] Elastin-like polypeptides (ELPs) are large, nonpolar polypeptides under investigation as components of a novel drug delivery system. ELPs are soluble at low temperatures, but they desolvate and aggregate above a transition temperature (T(T)). This aggregation is being utilized for...
Autores principales: | Lyons, Daniel F., Le, Vu, Kramer, Wolfgang H., Bidwell, Gene L., Lewis, Edwin A., Raucher, Drazen, Correia, John J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985474/ https://www.ncbi.nlm.nih.gov/pubmed/24450599 http://dx.doi.org/10.1021/bi400955w |
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