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Intradimer/Intermolecular Interactions Suggest Autoinhibition Mechanism in Endophilin A1

[Image: see text] Endophilin A1 is a homodimeric membrane-binding endocytic accessory protein with a high dimerization affinity. Its function has been hypothesized to involve autoinhibition. However, the autoinhibition mechanism, as well as the physicochemical basis for the high dimerization affinit...

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Detalles Bibliográficos
Autores principales: Chen, Zhiming, Chang, Ken, Capraro, Benjamin R., Zhu, Chen, Hsu, Chih-Jung, Baumgart, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985530/
https://www.ncbi.nlm.nih.gov/pubmed/24568626
http://dx.doi.org/10.1021/ja411607b