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A ribozyme that triphosphorylates RNA 5′-hydroxyl groups
The RNA world hypothesis describes a stage in the early evolution of life in which RNA served as genome and as the only genome-encoded catalyst. To test whether RNA world organisms could have used cyclic trimetaphosphate as an energy source, we developed an in vitro selection strategy for isolating...
Autores principales: | Moretti, Janina E., Müller, Ulrich F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985629/ https://www.ncbi.nlm.nih.gov/pubmed/24452796 http://dx.doi.org/10.1093/nar/gkt1405 |
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