Cargando…

PARP1–TDP1 coupling for the repair of topoisomerase I–induced DNA damage

Poly(ADP-ribose) polymerases (PARP) attach poly(ADP-ribose) (PAR) chains to various proteins including themselves and chromatin. Topoisomerase I (Top1) regulates DNA supercoiling and is the target of camptothecin and indenoisoquinoline anticancer drugs, as it forms Top1 cleavage complexes (Top1cc) t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Das, Benu Brata, Huang, Shar-yin N., Murai, Junko, Rehman, Ishita, Amé, Jean-Christophe, Sengupta, Souvik, Das, Subhendu K., Majumdar, Papiya, Zhang, Hongliang, Biard, Denis, Majumder, Hemanta K., Schreiber, Valérie, Pommier, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985661/ https://www.ncbi.nlm.nih.gov/pubmed/24493735 http://dx.doi.org/10.1093/nar/gku088

Ejemplares similares

PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes
por: Rehman, Ishita, et al.
Publicado: (2018)

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1
por: Zeng, Zhihong, et al.
Publicado: (2012)

Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells
por: Das, Subhendu K., et al.
Publicado: (2016)

Novel TDP2-ubiquitin interactions and their importance for the repair of topoisomerase II-mediated DNA damage
por: Rao, Timsi, et al.
Publicado: (2016)

TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining
por: Kawale, Ajinkya S, et al.
Publicado: (2018)

Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA
por: Rosa, Ilaria Dalla, et al.
Publicado: (2009)

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation
por: Zarkovic, Gabriella, et al.
Publicado: (2018)

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites
por: Lin, Xiaohui, et al.
Publicado: (2022)

Poly(ADP-ribose) polymerase and XPF–ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells
por: Zhang, Yong-Wei, et al.
Publicado: (2011)

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1
por: Langelier, Marie-France, et al.
Publicado: (2014)

Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo
por: Cho, Jang-Eun, et al.
Publicado: (2016)

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo
por: Shao, Zhengping, et al.
Publicado: (2020)

Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin
por: Hanzlikova, Hana, et al.
Publicado: (2017)

Condensin aids sister chromatid decatenation by topoisomerase II
por: Charbin, Adrian, et al.
Publicado: (2014)

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate
por: Ström, Cecilia E., et al.
Publicado: (2011)

Neutral Porphyrin Derivative Exerts Anticancer Activity by Targeting Cellular Topoisomerase I (Top1) and Promotes Apoptotic Cell Death without Stabilizing Top1-DNA Cleavage Complexes
por: Das, Subhendu K., et al.
Publicado: (2017)

Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis
por: Maskey, Reeja S., et al.
Publicado: (2017)

The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities
por: Kumar, Rupesh, et al.
Publicado: (2021)

The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions
por: Bilkis, Rabeya, et al.
Publicado: (2023)

Restriction of AID activity and somatic hypermutation by PARP-1
por: Tepper, Sandra, et al.
Publicado: (2019)

The α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells
por: Farr, Christine J., et al.
Publicado: (2014)

Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks
por: Szlachta, Karol, et al.
Publicado: (2020)

PARP1 suppresses homologous recombination events in mice in vivo
por: Claybon, Alison, et al.
Publicado: (2010)

RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression
por: Ramamoorthy, Mahesh, et al.
Publicado: (2012)

Inhibition of DNA damage repair by artificial activation of PARP with siDNA
por: Croset, Amelie, et al.
Publicado: (2013)

ARF induction in response to DNA strand breaks is regulated by PARP1
por: Orlando, Giulia, et al.
Publicado: (2014)

PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress
por: Schleicher, Emily M, et al.
Publicado: (2018)

PARP1 associates with R-loops to promote their resolution and genome stability
por: Laspata, Natalie, et al.
Publicado: (2023)

PARP1 proximity proteomics reveals interaction partners at stressed replication forks
por: Mosler, Thorsten, et al.
Publicado: (2022)

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways
por: Beck, Carole, et al.
Publicado: (2014)

DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1
por: Calkins, Anne S., et al.
Publicado: (2013)

Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage
por: Steffen, Jamin D., et al.
Publicado: (2016)

ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition
por: Giovannini, Sara, et al.
Publicado: (2020)

DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts
por: Gaggioli, Vincent, et al.
Publicado: (2013)

Topoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter
por: Cho, Jang-Eun, et al.
Publicado: (2015)

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase
por: Cerritelli, Susana M, et al.
Publicado: (2020)

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
por: Cheng, Qiao, et al.
Publicado: (2011)

The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
por: Fenton, Amanda L., et al.
Publicado: (2013)

The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
por: Orta, Manuel Luis, et al.
Publicado: (2014)

PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage
por: Riccio, Amanda A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_u2dciqb1oe43i4cds27fjli1tg