Cargando…

Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1

Mammalian cryptochromes (Crys) are essential circadian clock factors implicated in diverse clock-independent physiological functions, including DNA damage responses. Here we show that Cry1 modulates the ATR-mediated DNA damage checkpoint (DDC) response by interacting with Timeless (Tim) in a time-of...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Tae-Hong, Leem, Sun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985666/
https://www.ncbi.nlm.nih.gov/pubmed/24489120
http://dx.doi.org/10.1093/nar/gku094