Role of histone modifications and early termination in pervasive transcription and antisense-mediated gene silencing in yeast

Most genomes, including yeast Saccharomyces cerevisiae, are pervasively transcribed producing numerous non-coding RNAs, many of which are unstable and eliminated by nuclear or cytoplasmic surveillance pathways. We previously showed that accumulation of PHO84 antisense RNA (asRNA), in cells lacking t...

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Detalles Bibliográficos
Autores principales: Castelnuovo, Manuele, Zaugg, Judith B., Guffanti, Elisa, Maffioletti, Andrea, Camblong, Jurgi, Xu, Zhenyu, Clauder-Münster, Sandra, Steinmetz, Lars M., Luscombe, Nicholas M., Stutz, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985671/
https://www.ncbi.nlm.nih.gov/pubmed/24497191
http://dx.doi.org/10.1093/nar/gku100

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