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Hsp90 Inhibitors, Part 2: Combining Ligand-Based and Structure-Based Approaches for Virtual Screening Application

[Image: see text] Hsp90 continues to be an important target for pharmaceutical discovery. In this project, virtual screening (VS) for novel Hsp90 inhibitors was performed using a combination of Autodock and Surflex-Sim (LB) scoring functions with the predictive ability of 3-D QSAR models, previously...

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Detalles Bibliográficos
Autores principales:	Caroli, Antonia, Ballante, Flavio, Wickersham, Richard B., Corelli, Federico, Ragno, Rino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985681/ https://www.ncbi.nlm.nih.gov/pubmed/24555544 http://dx.doi.org/10.1021/ci400760a

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