Tungsten-Catalyzed Asymmetric Epoxidation of Allylic and Homoallylic Alcohols with Hydrogen Peroxide

[Image: see text] A simple, efficient, and environmentally friendly asymmetric epoxidation of primary, secondary, tertiary allylic, and homoallylic alcohols has been accomplished. This process was promoted by a tungsten–bishydroxamic acid complex at room temperature with the use of aqueous 30% H(2)O...

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Detalles Bibliográficos
Autores principales: Wang, Chuan, Yamamoto, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985688/
https://www.ncbi.nlm.nih.gov/pubmed/24422626
http://dx.doi.org/10.1021/ja411379e
Descripción
Sumario:[Image: see text] A simple, efficient, and environmentally friendly asymmetric epoxidation of primary, secondary, tertiary allylic, and homoallylic alcohols has been accomplished. This process was promoted by a tungsten–bishydroxamic acid complex at room temperature with the use of aqueous 30% H(2)O(2) as oxidant, yielding the products in 84–98% ee.

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