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Two Regions of the Ryanodine Receptor Calcium Channel Are Involved in Ca(2+)-Dependent Inactivation
[Image: see text] Skeletal (RyR1) and cardiac muscle (RyR2) isoforms of ryanodine receptor calcium channels are inhibited by millimollar Ca(2+), but the affinity of RyR2 for inhibitory Ca(2+) is ∼10 times lower than that of RyR1. Previous studies demonstrated that the C-terminal quarter of RyR has c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985739/ https://www.ncbi.nlm.nih.gov/pubmed/24521037 http://dx.doi.org/10.1021/bi401586h |