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Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria

[Image: see text] Cationic Antimicrobial Peptides (CAMPs) represent a first line of defense against bacterial colonization. When fighting Gram-negative bacteria, CAMPs initially interact electrostatically with the negatively charged phosphate groups in lipid A and are thought to kill bacteria by dis...

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Detalles Bibliográficos
Autores principales: Lee, Myeongseon, Sousa, Marcelo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985747/
https://www.ncbi.nlm.nih.gov/pubmed/24460375
http://dx.doi.org/10.1021/bi4015677

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