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Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin

[Image: see text] We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin protein with three states. Two nonfluorescent states, D(1) and...

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Detalles Bibliográficos
Autores principales: Venkatachalam, Veena, Brinks, Daan, Maclaurin, Dougal, Hochbaum, Daniel, Kralj, Joel, Cohen, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985752/
https://www.ncbi.nlm.nih.gov/pubmed/24428326
http://dx.doi.org/10.1021/ja411338t